Around 1.5 percent of women are likely to develop ovarian cancer at some stage of their life. It is less common than breast cancer but is considered as the most serious and fatal of all gynecological cancers.

The reason for this is that the cancer is usually advanced before it is diagnosed, making treatment difficult. The ovaries cannot be easily examined and, because the warning signs are unclear, late diagnosis is common.

Because of the lack of screening tests available, it is imperative to know the early symptoms and the possible risk factors.

Understanding ovarian cancer

The ovaries are two small organs that are a part of the female reproductive system and they are situated each side of the uterus. These ovaries contain germ cells that become eggs which are released when the woman menstruates.

They also produce estrogen and progesterone, the hormones that adjust the menstrual cycle and have an effect on the growth of breasts and body hair as well as affecting the development of the female body shape.

What types of tumors are there?

This normally happens in an organised manner but occasionally they grow abnormally and form a growth that we know as a tumor.

This tumor may be benign or it may be malignant. If it is benign, it is not cancerous and does not spread to other parts of the body. A malignant tumor, on the other hand, is cancerous and will often spread, making mestastases or secondary cancers.

Ovarian cancer is malignant and can occur in either one or both of the ovaries. There are three main groups that are related to the cells where the cancer starts.

Epithelial ovarian cancer, as its name implies, grows in the epithelium which is the surface of the ovary. It is the most common and accounts for around 90 percent of ovarian cancer. It mainly affects post menopausal women.

Another kind of epithelial tumor is a borderline tumor which grows much more slowly than its regular counterpart. These can normally be removed successfully even if diagnosed at an advanced stage.

There is a very rare form of ovarian cancer called germ cell ovarian cancer that starts in the cells that develop into eggs. This only accounts for about 5 percent of ovarian cancers and usually occurs only in women under 30.

The other five percent of ovarian cancers are generally sex-chord stromal cell ovarian cancer that affects the ovary cells responsible for female hormones. It can affect women of all ages.

Who is at risk of getting ovarian cancer?

The cause of ovarian cancer is unknown but there are some risk factors that have been identified through research. Although having these risk factors may increase your chances of developing ovarian cancer, they do not mean that you will necessarily get the disease. However, knowledge of these risk factors can be helpful. If you are concerned by having any of these risk factors, it is important to talk to your healthcare professional.

Factors that may increase your risk of ovarian cancer include:

Age- Around 90 percent of ovarian cancers affect women over 40.

Cultural background – Caucasian women in western society have higher rates of ovarian cancer than African or Asian women.

Number of pregnancies – Women who have never been pregnant appear to have a higher risk of ovarian cancer.

Family history – Between 5 and 10% of ovarian cancers are genetic. Researchers believe that the genes responsible for breast cancer (BRCA1 and BRCA2) are involved in almost all cases of familial ovarian cancer as well as familial breast cancer. It is also thought that these same damaged genes may be responsible for some endometrial and colon cancers. If you are genetically predisposed to any ovarian, breast, endometrial or colon cancers, you may have an increased risk of getting ovarian cancer.

Infertility and taking fertility drugs – Women who have had fertility drugs may be at a higher risk although infertility itself is a risk factor so this cannot be taken as a clear indication.

Hormone Replacement Therapy – The use of estrogen only HRT which is usually when you have had a hysterectomy, has been identified as a possible risk factor for ovarian cancer, particularly if you have been on this therapy for over ten years.

Lifestyle factors – Obesity is a risk factor associated with ovarian cancer as is a diet that is high in fat.

Can I reduce the risk of ovarian cancer?

Currently, there are no known procedures to prevent or detect early ovarian cancer but there are ways to reduce the risks. Some of these are:

Oral contraceptives – Research has found that the use of oral contraceptives can cut the risk of ovarian cancer by up to 60 percent if taken for a period of five years during your life.

Pregnancy and breastfeeding – Breastfeeding delays ovulation after childbirth and therefore decreases your risk of ovarian cancer. However, there is no guarantee that breastfeeding will stop you from developing ovarian cancer.

Enjoy a low fat diet – A high fat diet has been identified as a risk factor in ovarian cancer. Therefore, it makes sense to stick to a low fat diet with lots of fresh fruit and vegetables.

Tubal ligation or hysterectomy – These operations are only performed with a valid medical reason but it is believed that they both reduce the risk of ovarian cancer.

People with a strong family history of ovarian cancer may opt to speak to a genetic counselor that can assess whether you are at risk of developing the disease. If your family history suggests the damaged genes associated with ovarian, breast, endometrial, or colon cancer, it may be wise to have genetic testing. If these tests show the damaged BRCA1 or BRCA2 genes, you may be refe.rred to a gynecological oncologist to consider ways to reduce your risk.

Early symptoms of ovarian cancer

Because there is no screening test available for ovarian cancer, it is recommended that you have a regular pelvic vaginal checkup to see if there are any changes in your ovaries. It is also vital that you consult your healthcare specialist if you notice any possible signs of this illness. Because the symptoms are often common to many other medical conditions, diagnosis of ovarian cancer can be difficult

However, if you have any of the following symptoms that are unusual for you and that persist for more than a week, see your doctor without delay.

Some symptoms of ovarian cancer may include:

Stomach discomfort of pain in the pelvic area

Persistent nausea or wind.

Feeling constantly bloated or ‘full’.

Unexplained weight gain.

Loss of appetite or unexplained weight loss

Bowel changes

Frequency or urgency in urination

Lethargy.

Pain during intercourse.

Unexplained vaginal bleeding.

Sometimes, ovarian cancers are wrongly diagnosed as irritable bowel syndrome or menopause so if you are concerned, ask to be referred to a gynecological oncologist who can order tests to rule out ovarian cancer. It is rare that these symptoms will be ovarian cancer but if it is, early detection gives an excellent chance of survival.

Diagnosing ovarian cancer

If your doctor suspects ovarian cancer, you will be referred to a gynecological oncologist who will organize tests which may include any or all of the following:

An internal pelvic examination.

Blood tests

Chest and stomach x-rays.

A barium enema to rule out bowel problems

Ultrasound scans

If the results show a likelihood of ovarian cancer, you will be recommended to have an operation to confirm the diagnosis (none of the abovementioned tests can be sure). During the operation, if the surgeon finds ovarian cancer, they will normally remove the cancer as well as the ovaries.

It is important to understand before the surgery that this may happen so learn all you can about your illness and the outcomes before the operation.

Anne Wolski has worked in the health and welfare industry for more than 30 years. She is a co-director of http://www.magnetic-health-online.com and http://www.betterhealthshoppe.com which are both information portals with many interesting medical articles. She is also an associate of http://www.timzbiz.com which features many articles on internet marketing and resources.

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A symptom is an indication of disease, illness, injury, or that something is not right in the body. Symptoms are felt or noticed by a person, but may not easily be noticed by anyone else. For example, chills, weakness, achiness, shortness of breath, and a cough may be symptoms of pneumonia. A sign is also an indication that something is not right in the body. But signs are defined as things that can be seen by a doctor, nurse, or other health care professional. Fever, rapid breathing rate, and abnormal breathing sounds heard through a stethoscope may be signs of pneumonia.

Having one symptom or sign may not give enough information to suggest a cause. For example, a rash in a child could be a symptom of a number of things including poison ivy, an infectious disease like measles, an infection limited to the skin, or a food allergy. But if the rash is seen along with other signs and symptoms like a high fever, chills, achiness, and a sore throat, then a doctor can get a better picture of the illness. In many cases, a patient’s signs and symptoms do not give enough clues by themselves for the doctor to figure out the cause of an illness. Then medical tests, such as x-rays, blood tests, or a biopsy may be needed.

Cancer is a group of diseases that may cause almost any sign or symptom. The signs and symptoms will depend on where the cancer is, the size of the cancer, and how much it affects the nearby organs or structures. If a cancer spreads (metastasizes), then symptoms may appear in different parts of the body. As a cancer grows, it begins to push on nearby organs, blood vessels, and nerves. This pressure creates some of the signs and symptoms of cancer. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause early symptoms.

But sometimes cancers start in places where it does not cause any symptoms until the cancer has grown quite large. Pancreas cancers, for example, do not usually grow large enough to be felt from the outside of the body. Some pancreatic cancers do not cause symptoms until they begin to grow around nearby nerves (this causes a backache). Others grow around the bile duct, which blocks the flow of bile and leads to a yellowing of the skin known as jaundice. By the time a pancreatic cancer causes these signs or symptoms, it has usually reached an advanced stage.

A cancer may also cause symptoms such as fever, fatigue, or weight loss. This may be because cancer cells use up much of the body’s energy supply or release substances that change the body’s metabolism. Or the cancer may cause the immune system to react in ways that produce these symptoms. Sometimes, cancer cells release substances into the bloodstream that cause symptoms not usually thought to result from cancers. For example, some cancers of the pancreas can release substances which cause blood clots to develop in veins of the legs. Some lung cancers make hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.

Treatment is most successful when cancer is found as early as possible. Finding cancer early usually means it can be treated while it is still small and is less likely to have spread to other parts of the body. This often means a better chance for a cure, especially if initial treatment is to be surgery. A good example of the importance of finding cancer early is melanoma skin cancer. Skin cancer can be easy to remove if it has not grown deep into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly 100%. But once melanoma has spread to other parts of the body the survival rate drops dramatically.

Sometimes people ignore symptoms either because they do not know that the symptoms could mean something is wrong or because they are frightened by what they might mean and don’t want to seek medical help. General symptoms, such as fatigue, are more likely to have a cause other than cancer and can seem unimportant, especially if they have an obvious cause or only last a short time. In a similar way, a person may reason that a more specific symptom like a breast mass is probably a cyst that will go away by itself. But neither of these symptoms should be discounted or overlooked, especially if they have been present for a long time or are getting worse.

Most likely, any symptoms you may have will not be caused by cancer, but it’s important to have them checked out by your doctor, just in case. If cancer is not the cause, your doctor can help figure out what is and treat it, if needed. In some cases it is possible to detect some cancers before symptoms occur. The American Cancer Society and other health groups encourage the early detection of certain cancers before symptoms occur by recommending a cancer-related check-up and specific tests for people who do not have any symptoms. Keep in mind, however, that these recommended tests do not decrease the importance of reporting any symptoms to your doctor.

It is important to know what some of the general (non-specific) signs and symptoms of cancer are, but remember that having any of these does not mean that you have cancer. There are many other conditions that can cause these signs and symptoms, too. Most people with cancer will lose weight at some time with their disease. An unexplained (unintentional) weight loss of 10 pounds or more may be the first sign of cancer, particularly cancers of the pancreas, stomach, esophagus, or lung.

Fever is very common with cancer, but is more often seen in advanced disease. Almost all patients with cancer will have fever at some time, especially if the cancer or its treatment affects the immune system and makes it harder for the body to fight infection. Less often, fever may be an early sign of cancer, such as with leukemia or lymphoma. Fatigue may be an important symptom as cancer progresses. It may happen early, though, in cancers such as with leukemia, or if the cancer is causing an ongoing loss of blood, as in some colon or stomach cancers. Pain may be an early symptom with some cancers such as bone cancers or testicular cancer. But most often pain is a symptom of advanced disease. Along with cancers of the skin, some internal cancers can cause skin signs that can be seen. These changes include the skin looking darker (hyper pigmentation), yellow (jaundice), or red (erythema); itching; or excessive hair growth.Along with the above general symptoms, you should watch for the following common symptoms, which could be an indication of cancer. Again, there may be other causes for each of these, but it is important to bring them to your doctor’s attention as soon as possible so that they can be investigated.

Long-term constipation, diarrhea, or a change in the size of the stool may be a sign of colon cancer. Pain with urination, blood in the urine, or a change in bladder function (such as more frequent or less frequent urination) could be related to bladder or prostate cancer. Any changes in bladder or bowel function should be reported to your doctor. Skin cancers may bleed and look like sores that do not heal. A long-lasting sore in the mouth could be an oral cancer and should be dealt with right away, especially in patients who smoke, chew tobacco, or frequently drink alcohol. Sores on the penis or vagina may either be signs of infection or an early cancer, and should not be overlooked.

Unusual bleeding can happen in either early or advanced cancer. Blood in the sputum (phlegm) may be a sign of lung cancer. Blood in the stool (or a dark or black stool) could be a sign of colon or rectal cancer. Cancer of the cervix or the endometrium (lining of the uterus) can cause vaginal bleeding. Blood in the urine may be a sign of bladder or kidney cancer. A bloody discharge from the nipple may be a sign of breast cancer. Many cancers can be felt through the skin, mostly in the breast, testicle, lymph nodes (glands), and the soft tissues of the body. A lump or thickening may be an early or late sign of cancer. Any lump or thickening should be reported to your doctor, especially if you’ve just discovered it or noticed it has grown in size.

While they commonly have other causes, indigestion or swallowing problems may be a sign of cancer of the esophagus, stomach, or pharynx (throat). Any wart, mole, or freckle that changes in color, size, or shape, or loses its definite borders should be reported to your doctor without delay. The skin lesion may be a melanoma which, if diagnosed early, can be treated successfully. A cough that does not go away may be a sign of lung cancer. Hoarseness can be a sign of cancer of the larynx (voice box) or thyroid. While the signs and symptoms listed above are the more common ones seen with cancer, there are many others that are less common and are not listed here. If you notice any major changes in the way your body functions or the way you feel, especially if it lasts for a long time or gets worse, let your doctor know. If it has nothing to do with cancer, your doctor can investigate it and treat it, if needed. If it is cancer, you’ll give yourself the best chance to have it treated early, when treatment is most likely to be effective.

 

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